A study of effect of Vitamin D supplementation inOsteoarthritis patients

  • Dr.J. Ashok Vardhan Reddy Associate Professor, Department of Orthopedics, Maheshwara Medical College & Hospital, Chitkul, Sangareddy district, Telangana, India
  • Dr. Sridhar Garikapati Assistant Professor, Department of Orthopedics, Shadan Institute of Medical Sciences & Research Centre, Peeranchetuvu, Himayathnagar Road, Rangareddy district, Hyderabad, Telangana, India
Keywords: Osteoarthritis, Vitamin D, articular cartilage, malalignment

Abstract

Introduction: Osteoarthritis (OA) is the common cause of musculoskeletal disability and pain. Osteoarthritis (OA) is a chronic disease characterized by a loss of articular cartilage and changes of the subchondral bone. Lower levels of vitamin D were associated with greater knee pain, poor quadriceps function with poor physical function. Several studies have documented that vitamin D supplementation increases muscle strength, improve physical performance, and decreases risk of falls among older people with low level of serum vitamin D.

Materials &Methods:This present study was conducted at the outpatient clinic of the Department ofOrthopedics at Maheswara Medical college & Hospital, Sangareddy during a February–December 2017 study period.The inclusion criteria were that the participants had symptomatic knee OA and low vitamin D status (25(OH)D < 30 ng/mL).

Results:Data were analyzed using SPSS Statistics version 22 (SPSS, Inc., Chicago, IL, USA). Comparisonof baseline vs. post-vitamin Dsupplementation data was performed by paired t-test. One-wayrepeated-measurement ANOVA was used to test the time differences in muscle strength and physicalperformance. A p-value less than 0.05 for differences and the values were considered to be statistically significant.Dominant grip strength (p = 0.01) and overall physical performance, such as gait speed (p < 0.001),TUGT (p < 0.001), STS (p < 0.001), and 6MWT (p < 0.001), significantly improved after vitamin.

Conclusion:Nevertheless, vitamin D supplementation is a safe and inexpensive way to improve muscle strength and physical function in this population. Based on these findings, we recommend vitamin D supplementation in knee OA patients that have poor physical function.

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A study of effect of Vitamin D supplementation inOsteoarthritis patients
CITATION
DOI: 10.17511/ijoso.2018.i02.06
Published: 2018-06-30
How to Cite
Vardhan Reddy, J. A., & Garikapati, S. (2018). A study of effect of Vitamin D supplementation inOsteoarthritis patients. Surgical Review: International Journal of Surgery, Trauma and Orthopedics, 4(2), 90-93. https://doi.org/10.17511/ijoso.2018.i02.06
Section
Original Article