A study to correlation serum C reactive protein and bilirubin in appendicitis individuals in a tertiary health care setup
Abstract
Introduction: Acute appendicitis (AA) is one of the commonest surgical conditions. CT scan iswidely used for the diagnosis of AA. Different studies reported the utility of CRP and serum bilirubin(SB) in the diagnosis of AA. With this background, a study was conducted to find the diagnosticaccuracy of SB and CRP in the diagnosis of AA.
Materials and methods: The study was conductedin the Department of General Surgery, Konaseema Insititute of Medical Sciences and ResearchFoundation, Amalapuram for 18 months. Individuals AA were included. Those with a history ofjaundice, liver diseases, chronic alcoholism were not considered in this research. Initially, all weresubjected to thorough clinical examination and mantrel score (MS) was defined. USG abdomen, liverfunction tests, CRP were evaluated. Serum bilirubin (SB) and liver enzymes were estimated. A latexagglutination test was used to estimate CRP in the blood. Based on the clinical condition of the studyparticipant appendicectomy was carried out. Chi-Square test. P less than or equal to 0.05 wasconsidered statistically significant.
Results: A total of 60 participants were included. Gender wise,the male-female ratio was 1.85. The mean MS was 8.142, 8.714 and 9.444, respectively for AA,gangrenous appendicitis (GA) and perforated appendicitis (PA); statistically, there was no significantdifference. SB was evaluated, the mean values were 0.91+0.28mg/dl, 1.31+0.22 mg/dl and2.03+1.06 mg/dl, respectively in AA, GA and PA; statistically, there was a significant difference(P<0.05).
Conclusion: Appendicitis is common among males. The MS was an important indicatorfor the diagnosis of appendicitis with elevated SB and CRP
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